1,3-Pyrrolidinedicarboxylic acid, 4-amino-, 1-(1,1-dimethylethyl) 3-ethyl ester, (3R,4S)-rel- - Names and Identifiers
Name | O1-tert-butyl O3-ethyl (3S,4R)-4-aminopyrrolidine-1,3-dicarboxylate
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Synonyms | LogP trans-1-tert-Butyl 3-ethyl 4-aMinopyrrolidine-1,3-dicarboxylate (3S,4R)-1-TERT-BUTYL 3-ETHYL 4-AMINOPYRROLIDINE-1,3-DICARBOXYLATE trans-4-aMino-1-(tert-butoxycarbonyl)pyrrolidine-3-carboxylic acid O1-tert-butyl O3-ethyl (3S,4R)-4-aminopyrrolidine-1,3-dicarboxylate rel-1-tert-butyl 3-ethyl (3R,4S)-4-aminopyrrolidine-1,3-dicarboxylate Rel-(3R,4S)-1-tert-Butyl 3-ethyl-4-aminopyrrolidine-1,3-dicarboxylate (3R,4S)-rel-1-tert-Butyl 3-ethyl 4-aMinopyrrolidine-1,3-dicarboxylate 1,3-Pyrrolidinedicarboxylic acid, 4-amino-, 1-(1,1-dimethylethyl) 3-ethyl ester, (3R,4S)-rel-
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CAS | 362489-56-3
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InChI | InChI=1/C12H22N2O4/c1-5-17-10(15)8-6-14(7-9(8)13)11(16)18-12(2,3)4/h8-9H,5-7,13H2,1-4H3/t8-,9-/m0/s1 |
1,3-Pyrrolidinedicarboxylic acid, 4-amino-, 1-(1,1-dimethylethyl) 3-ethyl ester, (3R,4S)-rel- - Physico-chemical Properties
Molecular Formula | C12H22N2O4
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Molar Mass | 258.31 |
Density | 1.129±0.06 g/cm3(Predicted) |
Boling Point | 336.5±42.0 °C(Predicted) |
Flash Point | 157.3°C |
Vapor Presure | 0.000112mmHg at 25°C |
pKa | 8.85±0.40(Predicted) |
Storage Condition | 2-8°C(protect from light) |
Refractive Index | 1.488 |
1,3-Pyrrolidinedicarboxylic acid, 4-amino-, 1-(1,1-dimethylethyl) 3-ethyl ester, (3R,4S)-rel- - Introduction
O1-tert-butyl O3-ethyl (3S,4R)-4-aminopyrrolidine-1,3-dicarboxylate is an organic compound whose chemical name is O1-tert-butyl O3-ethyl (3S,4R)-4-aminopyrrolidine-1,3-dicarboxylate.
The compound is a white crystalline solid, hardly soluble in water at normal temperature, and soluble in organic solvents such as ethanol and dichloromethane.
O1-tert-butyl O3-ethyl (3S,4R)-4-aminopyrrolidine-1,3-dicarboxylate is commonly used as a protecting group in organic synthesis. Boc is short for t-butyloxycarbonyl (tert-butoxycarbonyl), which can be used to protect the amine group from side reactions and can be removed when desired. This method of protection is widely used in peptide synthesis and drug synthesis.
the preparation method of O1-tert-butyl O3-ethyl (3S,4R)-4-aminopyrrolidine-1,3-dicarboxylate can be obtained by reacting pyrrolidine with dimethylpyrrolidone and then through protection reaction.
Regarding safety information, although the compound has low toxicity under general operation, it should still be handled carefully in the chemical laboratory. Avoid contact with skin, eyes and inhalation, and take personal protective measures such as gloves, goggles and respiratory protection if necessary. The safety data sheet should be read and followed before any operation.
Last Update:2024-04-09 20:02:46